DEXTRAN

DEXTRAN


 It is a polysaccharide produced by growing bacteria on the substrate sucrose, Containing a backbone of D-glucose units linked predominantly α-D (1-6).


 Commercially LeuconostOC mesenteroides and Leuconostoc dextranicum organisms are used.


 Various grades of dextrans are produced depending upon the method used for preparation.
Dextrans are water soluble and insoluble in alcohol. Molecular weight of dextrans varies from - 75000. All dextrans exclusively contain α -D-glucopyranosyl units.


Uses

1.      Dextran is used as plasma volume expander.

2.      Dextran 40 is also used as blood flow adjuvant.

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